Editor’s Pick
MAY 26, 2011 9:30AM
A Significant Clue to Understanding the Complexity of Autism
Any disease which reportedly has increased by more than ten times in a decade should cause a major alarm. Autism is a cruel communication dysfunction that has this distressing rate of increase. The actual numbers worldwide may be more than this ten time increase. Accurate, reliable documentation is simply not available for many countries. Such statistics are not kept.
Autism is a wide spectrum brain disorder. The complexity of autism is that for each child with autism appears to have unique variables. The commonality is that there are problems with communication and interpersonal relationships. This ranges from mild to severe. Researchers have postulated that even some adequately functioning individuals may have a form of autism with repetitive mannerisms.
This range of variability illustrates one of the major problems with treating autism. The search has been for some commonality which causes these problems. A neurological study published in Nature may offer such a clue:
"... The scientists in the UK, US and Canada compared samples from 19 autistic brains and 17 healthy ones.
They noticed that 209 genes linked to the way brain cells work and talk to each other were working at a lower level in autistic brains while 235 genes linked to immune and inflammatory responses were expressed more strongly."
The study identifies a noted difference in autistic brains and the loci of these differences. It is in the frontal and temporal lobes.
The obvious criticism of this research will focus on the small sample size. Questions of validity and reliability of any findings will be scrutinized closely, due to the complex nature of autism. However, the findings are significant in identifying possible processing problems at a genetic level. It may lead to more effective means to address a presenting problem along the autism spectrum. The hope would be to understand what is causing this staggering increase in this information processing dysfunction. The ultimate challenge is to understand underlying causes to prevent another tenfold increase in autism during the next decade.
Catherine Forsythe
some additional links:


Salon.com
Comments
Great article and rated with hugs
what are the odds that it will all be traced down to some human-generated pathogen?
rated with love